Note: Currently only available through a bundled series of lectures
Early Breastmilk Exposure and Later Cardiovascular Health in Premature Infants
by Afif EL-Khuffash, MB, BCh, BAO, BA (Sci), FRCPI, MD, DCE, IBCLC
Duration: 60 Mins
Credits: 1 CERP, 1 L-CERP, 1 Nurse Contact Hours
Handout: Yes
Abstract:
Premature infants have impaired cardiovascular function that persists into adulthood. Preterm infants exhibit impaired systolic and diastolic dysfunction that is intolerant of the adverse loading conditions experienced during the early neonatal period. Young adults born premature demonstrate a unique cardiac phenotype characterized by reduced biventricular volume, relatively lower systolic and diastolic function, and a disproportionate increase in muscle mass. This may clinically manifest by an increased risk of cardiovascular incidents, hypertension, and reduced exercise tolerance. Those consequences appear to result from early postnatal cardiac remodelling due to premature birth and associated comorbidities. Recent evidence suggests that early exposure to breast milk slows down or even arrests those pathophysiological changes, thereby mitigating the long-term adverse effects of premature birth on cardiovascular health. In this presentation, I aim to demonstrate the vital role of early breast milk exposure in preventing cardiovascular disease in preterm infants. We will explore the emerging evidence and examine the possible mechanistic pathways mediating this phenomenon.
Learning Objectives:
1. Describe the characteristics of premature infants' cardiovascular system.
2. Explain the possible mechanisms facilitating the beneficial effect of breast-milk on preterm infants' cardiovascular health.
3. Describe the beneficial effects exposure to breast milk has on the maturation of the cardiovascular system in premature infants.
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