Speaker Type: Advancements in Neonatal Pharmacology Lecture Pack 2023
Country: United States of America
Biography:
M. Petrea Cober, PharmD, BCNSP, BCPPS, FASPEN, attended the University of Tennessee, College of Pharmacy in Memphis, Tennessee. She completed her PGY1 Pharmacy Residency at Penn State Milton S. Hershey Medical Center in Hershey, Pennsylvania, and her PGY2 Pharmacy Residency in Pediatrics at the University of Michigan Hospitals and Health System in Ann Arbor, Michigan. She is currently the Clinical Pharmacy Specialist - Neonatal Intensive Care Unit and PGY1 Residency Program Director at Akron Children's Hospital where she provides clinical services and precepts pharmacy students and PGY1 pharmacy residents. She is also a Professor in the Department of Pharmacy Practice at Northeast Ohio Medical University (NEOMED). Her didactic teaching is in the areas of pediatrics, women’s health, and nutrition. She was awarded the 2021 Stanley Serlick Award from the American Society for Parenteral and Enteral Nutrition (ASPEN) recognizing her contributions to parenteral nutrition safety and serves as the current Chair-elect of the ASPEN Parenteral Nutrition Safety Committee.
The lifetime risk of seizures is highest in the neonatal period. While the etiology of neonatal seizures is commonly the result of acute brain injury, other possibilities exist. Unfortunately, the need to treat neonatal seizures with anti-epileptic therapies or the timing and duration of therapeutic management is still vastly unknown. While phenobarbital has long been considered the mainstay of first-line medical therapy for neonatal seizures, newer agents are increasing in their popularity due to fewer side effects and concerns regarding potential neuronal apoptosis with phenobarbital. This presentation will discuss the etiology, need and timing for therapeutic management, compare and contrast various anti-epileptic therapies, and first-line, second-line, and therapies following initial failure for neonatal seizures.
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