Managing pain and discomfort in the neonatal patient is complex in many ways. Immature metabolic processes can lead to unpredictable effects that may lead to either negative effects and/or unsuccessful control of pain. As we have learned more about these metabolic pathways and how these medications are utilized, more evidence now exists that determine when one medication may be preferred over another depending on the clinical situation. Looking into the future of drug dosing, we may soon be able to determine a neonate's pharmacogenomic profile in order to provide true personalized medicine.
This presentation will help the learner understand the complexities of these challenges and provide them with the information and the tools to provide state-of-the-art medical care.
Learning Objectives:
Objective 1: Discuss the conditions that the neonate face and that cause pain and discomfort and which medications are the most appropriate depending on the clinical condition and patient parameters.
Objective 2: Identify the most commonly used medications for pain in the neonate and what factors would lead the caregiver to alter therapy and/or dose.
Objective 3: Describe the specific classes of pain medications that are appropriate for use in the neonate and describe the toxicities and administration issues.
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