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United Kingdom

Rebeccah Slater, BSc, MSc, PhD, Professor

  • Speaker Type: Pain Management in the NICU Lecture Pack 2019
  • Country: United Kingdom

2. Rebeccah Slater is a Senior Wellcome Trust Research Fellow and Professor of Paediatric Neuroscience at the University of Oxford. She is also a Professorial Fellow st St John’s College, Oxford. Rebeccah studied Physics (BSc) at Imperial College and Neuroscience (MSc) at UCL, and in 2007 was awarded her PhD at UCL under the supervision of Prof Maria Fitzgerald. Since 2013 Rebeccah has led the Paediatric Neuroimaging Research Group, which focuses on understanding the mechanisms that underlie the development of pain perception in the human infant. She uses a range of non-invasive brain imaging tools, including EEG and fMRI, to explore the development of pain perception. She has published many articles about infant pain and has been passionately involved in science communication and the public engagement of science. She has taken part in discussions on TV and radio, including BBC Radio 4 and the BBC World Service. Rebeccah holds an honorary research position in the Neonatal Care Services at the John Radcliffe Children’s Hospital and is a PI at the Wellcome Centre for Integrative Neuroimaging (WIN).

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The Development of Human Pain
Pain in infancy has negative long-term consequences and its prevention is a clinical priority, but adequate pain treatment requires mechanistic understanding of the structural and functional development of human pain-related brain circuitry. Recent scientific and technological advances provide insights into how noxious information is transmitted to the infant brain, providing a platform to ask how intrinsic brain network connectivity and the environment affect pain-related brain activity, behaviour and ultimately pain perception in the developing infant nervous system. As infants cannot describe their pain, we are reliant on alternative methods to measure their pain experience. My goal is to understand the mechanisms that drive and modulate pain perception in early human development. In this talk, I will discuss a series of mechanistic studies in human infants that aim to better understand the development of human pain. I will address fundamental questions regarding the functional development of pain-related brain activity and behavior, and will discuss whether inherent individual differences in how the infant brain behaves at rest drives differences in pain vulnerability. Finally, I will describe how these mechanistic insights can be used to test new analgesic treatment options and improve the treatment of infant pain.
Presentations: 5  |  Hours / CE Credits: 5  |  Viewing Time: 4 Weeks
Hours / CE Credits: 1 (details)  |  Categories: Pain Management in the NICU