When antibiotics were first broadly introduced in the 1930s, they were considered the most important advancement in modern medicine. Deaths attributed to communicable diseases were drastically reduced leading to the belief that infectious diseases were conquerable. Bacteria, however, counter antibiotic chemotherapy with resistance mechanisms that result in the emergence of infections untreatable by the current artillery of therapeutics. Efforts to develop new antimicrobial agents with unique structural motifs and novel modes of action to fight multi-drug resistant pathogens are ongoing. During this seminar, I will discuss our groups ongoing efforts to develop human milk oligosaccharides as novel antimicrobial agents.
Learning Objectives:
Objective 1: Understand the infection process;
Objective 2: Understand how children are protected via breast milk;
Objective 3: Understand what pathogens are currently priorities to defeat.
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