Intravenous lipid emulsions (ILE) are essential for promoting optimal nutrition in the neonatal intensive care unit. However, long-term use of a pure soybean lipid emulsion has been associated with potentially fatal complications such
as intestinal failure associated liver disease and fat overload syndrome. In the past decade, the science of lipid emulsions has progressed with a focus on optimizing nutrition and prevention of disease, Concerns on the use of these different oil sources on essential fatty acid status and growth
will be discussed. By providing an overview of the current literature, this lecture will provide a general overview of the currently available ILE and how differences in composition may impact the neonate.
Learning Objectives:
1: Describe how phytosterol and vitamin E content can influence how a neonate tolerates an intravenous lipid emulsion.
2: Describe how alternative lipid emulsions may impact neonatal and infant growth.
3: Describe how dosing varies based on the type of lipid emulsion product.
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