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Delayed Lactogenesis II In Women With Gestational Diabetes Mellitus

Background: Higher intensity and longer duration of breastfeeding is associated with protection against type 2 diabetes development. While exclusive breastfeeding is optimal, women with gestational diabetes mellitus (GDM) have lower exclusive breastfeeding rates than non-diabetic women. While women with GDM have expressed that they feel that their milk “comes in” late, there is limited biochemical validation of their perception and a lack of information regarding the difference in metabolite composition of colostrum which may influence the transition to lactogenesis II. Methods: Researchers conducted a prospective case-control pilot study involving the comparison of metabolite concentrations and maternal perception of milk “coming in” between postpartum women with GDM and without GDM. Results: There were lower concentrations of lactose and citrate, metabolites that indicate transition to lactogenesis II, in colostrum samples of women with GDM compared to non-diabetic women. Furthermore, a higher proportion of women with GDM reported a perceived delay in their milk “coming in.” Conclusions: Lower levels of lactose and citrate in the colostrum samples of women with GDM compared to those without GDM indicate delayed lactogenesis II with GDM which may suggest a biological mechanism associated with lower breastfeeding rates among women with GDM. Additionally, maternal perception of delayed lactogenesis II among women with GDM appears to be validated by biomarkers. The implications for practice relate to lactation support in the early postpartum period among women with GDM.

$18.00 USD
Total CE Hours: 1.00   Access Time: 2 Weeks  
Lectures in this bundle (1):
Duration: 60 mins
Ilana Azulay Chertok, PhD, RN, IBCLC
Delayed Lactogenesis II In Women With Gestational Diabetes Mellitus
Israel Ilana Azulay Chertok, PhD, RN, IBCLC

Dr. Ilana Azulay Chertok is a Professor and Associate Director of Nursing Research and Scholarship at the Ohio University, College of Health Sciences and Professions, School of Nursing. She earned her bachelor’s in international relations and nursing, master’s in nursing, doctorate (PhD) in epidemiology, and post-doctorate in nursing research. The primary focus of her research is national and global maternal-infant health, specifically lactation and breastfeeding research. She has published and presented her work in national and international journals, conferences, and other professional forums. Dr. Chertok has served as a mentor to undergraduate students, graduate students, and health professionals of various disciplines including nursing, medicine, and public health. Currently, she is the lead PI on a study examining the differences in breastfeeding and breast milk between women with and without gestational diabetes mellitus.

Objective 1: Explain the importance of breastfeeding for women with GDM;

Objective 2: List early breastfeeding challenges faced by women with GDM;

Objective 3: Use evidence-based lactation strategies to support women with GDM;

Israel Ilana Azulay Chertok, PhD, RN, IBCLC
Abstract:

Background: Higher intensity and longer duration of breastfeeding is associated with protection against type 2 diabetes development. While exclusive breastfeeding is optimal, women with gestational diabetes mellitus (GDM) have lower exclusive breastfeeding rates than non-diabetic women. While women with GDM have expressed that they feel that their milk “comes in” late, there is limited biochemical validation of their perception and a lack of information regarding the difference in metabolite composition of colostrum which may influence the transition to lactogenesis II. Methods: Researchers conducted a prospective case-control pilot study involving the comparison of metabolite concentrations and maternal perception of milk “coming in” between postpartum women with GDM and without GDM. Results: There were lower concentrations of lactose and citrate, metabolites that indicate transition to lactogenesis II, in colostrum samples of women with GDM compared to non-diabetic women. Furthermore, a higher proportion of women with GDM reported a perceived delay in their milk “coming in.” Conclusions: Lower levels of lactose and citrate in the colostrum samples of women with GDM compared to those without GDM indicate delayed lactogenesis II with GDM which may suggest a biological mechanism associated with lower breastfeeding rates among women with GDM. Additionally, maternal perception of delayed lactogenesis II among women with GDM appears to be validated by biomarkers. The implications for practice relate to lactation support in the early postpartum period among women with GDM.

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CERPs - Continuing Education Recognition Points
GOLD Conferences has been designated as a Long Term Provider of CERPs by the IBLCE--Approval #CLT114-07. Approved for 1 L-CERP.

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Tags / Categories

(IBCLC) Physiology and Endocrinology, Breastfeeding Complications

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